Time-Sensitive Indication

Hyperbaric Oxygen Therapy for Compromised Skin Grafts and Flaps

Compromised skin grafts and flaps are an FDA-cleared, UHMS-recognized indication for HBOT, and Medicare covers preparation and preservation of compromised skin grafts. Used early and alongside your surgeon's care, HBOT may support tissue survival while new blood vessels grow in. A physician determines, with your surgeon, whether it is appropriate.

Physician-directed care under Dr. Rajwinder Singh Bahia, MD · Updated

The Basics

How HBOT May Support Healing in Compromised Grafts and Flaps

Compromised skin grafts and flaps are an FDA-cleared indication and a UHMS-recognized indication for hyperbaric oxygen therapy. Medicare covers HBOT for the preparation and preservation of compromised skin grafts.

A skin graft is a thin layer of skin moved to a new spot with no blood supply of its own. For the first few days it survives by soaking up oxygen and nutrients from the wound bed beneath it. Then new blood vessels grow in and connect it. A flap is thicker tissue moved with its own blood vessels still attached, or reconnected under a microscope. If blood flow into or out of the flap is poor, the tissue can start to die.

Either way, the danger period is the same: the time before the tissue has a dependable blood supply. When oxygen runs short, the graft or flap can turn pale, dusky or congested and begin to fail. Restoring blood flow can also cause its own damage, called reperfusion injury.

During HBOT you breathe near-100% oxygen in a pressurized chamber, so much more oxygen dissolves in your blood plasma and can spread into nearby tissue. As an adjunct to surgical care, HBOT may support:

  • oxygen delivery to the tissue while new blood vessels form,
  • the growth of those new vessels,
  • reduced swelling in the area, and
  • less damage from reperfusion injury, based on laboratory and clinical research.

For more on the physics, read about oxygen delivery to compromised tissue.

Candidacy

Who Is a Candidate?

The key word is compromised. HBOT is considered for a graft or flap that is showing signs of trouble, or for a surgical site at high risk, not for every graft. Your surgeon usually recognizes the problem first. Signs can include:

  • skin that looks pale, dusky, bluish or mottled,
  • swelling or congestion, often with a purple color,
  • slow color return after gentle pressure (delayed capillary refill),
  • blistering, or loss of part of the graft or flap.

Patients are commonly referred by plastic and reconstructive surgeons, ear, nose and throat surgeons, oral surgeons, orthopedic surgeons and trauma teams. Situations include flaps after breast reconstruction, reconstruction after skin cancer removal, grafts after injuries or burns once the acute phase has passed, and surgery in previously irradiated tissue. For that last group, see flaps in irradiated tissue.

Routine recovery after cosmetic or other surgery is not a cleared indication. HBOT is not a way to speed up normal healing after a procedure.

Your physician determines whether HBOT is appropriate, in discussion with your surgeon. If a wound near a graft simply isn't closing, see non-healing surgical wounds.

Timing: why early matters

A failing graft or flap can change over hours to days. Published reviews of HBOT for compromised grafts and flaps emphasize starting as soon as compromise is recognized, because tissue that has already died cannot be rescued. If you are a patient, contact your surgeon first. If your surgeon suggests HBOT, or you are a surgeon's office, call (369) 222-0979 and tell us it is time-sensitive. Sessions are by appointment, and we will be straightforward about how quickly we can see you.

Dermal filler vascular occlusion

Rarely, a cosmetic filler injection can block a blood vessel and cut off blood supply to the skin. Warning signs include sudden pain, blanching or a blotchy, dusky pattern near the injection site, and any change in vision. This is an emergency. The first step is to contact the injector right away, since hyaluronic acid fillers are commonly dissolved with an enzyme called hyaluronidase. Any vision change needs an emergency room immediately. Case reports describe HBOT as an adjunct in some filler complications, but it is not the first-line response and is not a substitute for emergency care.

The Research

What the Evidence Shows

HBOT for grafts and flaps has a long history of use, but large modern randomized trials are limited. Surgeons face real ethical limits on withholding a possibly helpful treatment from tissue that is actively failing. These are findings from published research, not promises about any individual graft.

Key evidence for HBOT in compromised grafts and flaps. Findings from published research, not predicted results.
StudyYearDesignParticipantsFindingLimitation
Systematic review, Plastic and Reconstructive Surgery Global Open2026Review of 24 comparative studies (13 randomized trials)2,246All 13 randomized trials reported healing rates favoring HBOT; authors made strong recommendations for peri-operative HBOT in serious soft-tissue injuries needing flaps or grafts.Certainty of evidence very low to moderate; blinding was rarely possible.
Francis and Baynosa, Advances in Wound Care2017Narrative reviewNot applicableSummarizes how HBOT may support graft and flap survival, including effects on reperfusion injury.Draws heavily on animal and older clinical studies.
UHMS indications (15th ed.)2023Expert review of the evidenceNot applicableRecognizes compromised grafts and flaps as an indication for HBOT.Based on the same mixed-quality evidence.

The balance of evidence supports HBOT as a reasonable adjunct for compromised grafts and flaps, especially when started early. It does not show that HBOT can save every failing graft, and results depend on the cause of compromise, how much tissue has already been lost and the quality of surgical care.

Your Plan

What a Course Looks Like

At Generations Wellness, care is directed by Dr. Rajwinder Singh Bahia, MD. Sessions take place in hard-shell monoplace chambers, each for one person, where you breathe medical-grade oxygen at a physician-prescribed pressure while staff stay in communication with you.

  • Pressure: commonly 2.0 to 2.4 ATA, as prescribed by your physician.
  • Session length: about 90 to 120 minutes including pressurization and depressurization.
  • Course length: graft and flap courses are often shorter and more intensive than wound-care courses. Your physician sets the schedule with your surgeon, based on how the tissue looks and responds.
  • Monitoring: the surgical site is checked and photographed so changes can be tracked and shared with your surgeon.
  • Your surgeon stays in charge of dressings, drains, medications and any further surgery.

For a walk-through of a visit, read what a session involves.

Safety

Risks and Contraindications

HBOT is generally well tolerated under supervision, but it has side effects. The most common is ear or sinus pressure (barotrauma). Others include temporary nearsightedness that usually resolves after the course, tiredness and confinement anxiety. Oxygen-toxicity seizures are rare, at roughly 1 in 5,000 to 10,000 treatments.

After surgery, a few extra checks matter. The only absolute contraindication is an untreated collapsed lung, which is worth confirming after chest, breast or upper-body procedures or line placements. Recent ear or sinus surgery, certain chemotherapy drugs, some lung conditions and implanted devices also need review. Dressings, drains and anything that could hold heat or spark are checked against chamber safety rules. See contraindications for more.

Paying for Care

Cost and Insurance for Compromised Grafts and Flaps

Generations Wellness currently offers HBOT on a self-pay basis. We do not bill insurance, Medicare or Medi-Cal today while we work toward insurance contracts.

In general, this is one of the indications insurance may cover. Original Medicare's NCD 20.29 covers HBOT for the preparation and preservation of compromised skin grafts, though not for the primary management of wounds. At facilities that bill Medicare, patients typically pay the Part B deductible ($283 in 2026) and then 20% coinsurance. Commercial and Medicare Advantage plans commonly require prior authorization, which can take time, so ask your surgeon's office early.

Published national self-pay ranges for medical-grade HBOT at independent centers run about $150 to $450 per session. These are ranges, not quotes. We review pricing clearly at your consultation. Because timing matters here, if you have coverage that may apply, ask us and we'll explain your options honestly, including when a covered setting may be the better choice. See Medicare coverage for compromised grafts and HBOT cost.

For Surgeons

For Surgeons in the Central Valley

Plastic, reconstructive, head and neck, oral and orthopedic surgery in the region is performed at hospitals and surgical centers in Modesto, Stockton and surrounding communities. If you are caring for a patient with a compromised graft or flap, our physician can discuss the case with you and coordinate an assessment. You remain in charge of surgical care, and we share updates after sessions. Start with surgeon referral information, or call (369) 222-0979.

Important

A physician assessment is required before beginning HBOT at Generations Wellness. HBOT complements, and never replaces, the treatment prescribed by your doctors. If a graft or flap changes color or you develop fever, spreading redness or sudden pain, contact your surgeon right away.

Questions

Grafts, Flaps and HBOT: Frequently Asked Questions

Can HBOT save a failing skin graft?

It may improve the chance of salvage when started early as an adjunct to surgical care. Compromised grafts and flaps are an FDA-cleared indication, but no one can promise an outcome.

How soon after surgery should HBOT start?

As early as possible once compromise is recognized, because tissue that has already died cannot be rescued. Your surgeon and our physician decide together.

Is HBOT used after every skin graft or cosmetic surgery?

No. It is used for grafts and flaps that are compromised or at high risk. Routine recovery after surgery is not a cleared indication.

How many sessions are typical?

Graft and flap courses are often shorter and more intensive than wound courses. Your physician sets the plan with your surgeon based on how the tissue responds.

Does Medicare cover HBOT for a compromised graft?

Medicare's coverage policy includes preparation and preservation of compromised skin grafts. Generations Wellness currently offers self-pay care only, so ask us and we'll explain your options honestly.

Sources

  1. Systematic Review of Comparative Studies Evaluating Hyperbaric Oxygen Therapy on Skin Flap and Graft Surgical Indications. Plastic and Reconstructive Surgery Global Open. 2026. pmc.ncbi.nlm.nih.gov
  2. Francis A, Baynosa RC. Hyperbaric Oxygen Therapy for the Compromised Graft or Flap. Advances in Wound Care. 2017. pubmed.ncbi.nlm.nih.gov
  3. Centers for Medicare & Medicaid Services. National Coverage Determination 20.29, Hyperbaric Oxygen Therapy. cms.gov
  4. Undersea and Hyperbaric Medical Society. Hyperbaric Oxygen Therapy Indications. uhms.org
  5. U.S. Food and Drug Administration. Hyperbaric Oxygen Therapy: Get the Facts. fda.gov
  6. StatPearls. Hyperbaric Complications. ncbi.nlm.nih.gov
  7. MedlinePlus. Skin Graft. medlineplus.gov

This page is educational and not medical advice. Study results describe published research, not expected outcomes. A physician assessment is required before HBOT. See our full medical disclaimer.

Your Next Step

Begin With a Physician Assessment

Every course starts with an honest conversation and a physician assessment. No pressure, no obligation.

Prefer to talk? (369) 222-0979